In Vitro Screening of Antiviral Activity of Lactic Acid Bacteria Isolated from Traditional Fermented Foods

Studies of newly isolated strains lactic acid bacteria (LAB) are a good basis for expanding the potential their applications in functional foods, probiotic food supplements, and other products. They exhibit various properties, including such with antiviral activity. Probiotic can manifest effects by mechanisms, direct interaction viruses, production compounds, or immune system modulation. Ten LAB from traditional fermented products have been tested determination This study was performed to evaluate effect cell-free supernatants (CFSs) studied on viral replication Human alphaherpesvirus—HHV-1 HHV-2 as well virucidal The CFSs were used non-toxic concentrations 25%, 6.25%, 1.6%. No activity observed CFSs, but five well-defined inhibition selective index (SI) 4.40 >54. For two these strains, Lactobacillus delbrueckii subsp. bulgaricus KZM 2-11-3 Lactiplantibacillus plantarum KC 5-12 strong against over 45 detected, which is further research.